CLOMIFEN 25MG 50 TABLETS
CLOMID (active agent - clomiphene citrate) is a selective non-steroidal estrogen receptor (SERM) modulator of the triphenylethylene group. Clomiphene was developed and approved for use in the early 1970s to treat female infertility, and later expanded to treat male infertility as well.
In most cases, this SERM is used for post-cycle therapy (PCT) purposes, the use of which is intended to stimulate natural production of testosterone that has been suppressed through the use of anabolic steroids. Clomiphene stimulates the hypothalamus, which stimulates the anterior pituitary gland to release gonadotrophic hormones. Gonadotrophic hormones are follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH stimulates (in men) spermatogenesis and LH stimulates the leydig cells of the testicles to secrete more testosterone. This feedback mechanism is known as the hypothalamic-pituitary-testicular axis (HPTA), and results in an increase in the body's own production of testosterone. Blood levels rise to compensate for decreasing exogenous steroid levels. This is vital to minimize post-cycle muscle losses.
The average starting dose of clomiphene should be approximately 150 mg per day, and should be maintained at this level for 1-2 weeks. From there, it should drop to 100 mg for another 1-2 weeks, with the final dose of clomiphene falling to 25-50 mg per day during the last week of PCT. The exact doses depend on the individual and will be determined based on the results of the blood test.
TIP: The correct time to start clomiphene depends on the type and cycle of steroids you have been using. Different steroids have different half-lives (indicates how long a substance decreases in the blood), and the administration of clomiphene should be taken accordingly. If your cycle ends with any long ester base steroid, your starting dose of Clomos should start approximately two weeks after your last injection; If you are finished with all short ester base steroids, PCT will start approximately three days after your last injection. Clomiphene taken when blood levels of androgens are still high will be a waste. It is crucial to wait for androgen levels to drop before implementing post-cycle therapy. However, if taken too late, you could possibly lose muscle.
There are no special considerations for the administration of clomiphene. It can be administered before, during or after meals. It can also be consumed in the morning or at night before bed. There should be no reason to divide the clomiphene dose throughout the day, as the half-life of clomiphene is approximately 5 days, which is considered long enough to maintain stable blood levels over a 24-hour period ( or more) without having to divide tablets or doses.